Table 1 Characteristics of the whole study population (n = 2332).

From: Single Nucleotide Polymorphisms in the G-Protein Coupled Receptor Kinase 5 (GRK5) Gene are associated with Plasma LDL-Cholesterol Levels in Humans

n (females/males)

1469/863

Age (years)

40.0 [29.0–51.0]

BMI (kg∙m−2)

28.64 [24.24–35.85]

Waist circumference (cm)

96.0 [84.0–110.0]

Total body fat mass MRT (% BW)*

30.23 [23.52–37.82]

Visceral fat mass MRT (% BW)*

3.14 [1.89–4.30]

Liver fat MRS (%)**

3.37 [1.56–8.09]

Fasting glucose (mM)

5.11 [4.83–5.50]

2 h glucose OGTT

6.22 [5.22–7.28]

Fasting Insulin (pM)

60 [39–102]

2 h Insulin (pM)

360 [202–668]

Fasting free fatty acids (μM)

570 [429–724]

2 h free fatty acids (μM)

73 [47–113]

Fasting triglycerides (mg/dl)

102.0 [72.0–147.0]

Total cholesterol (mg/dl)

190.0 [166.0–216.0]

HDL-cholesterol (mg/dl)

51.0 [43.0–61.0]

LDL-cholesterol (mg/dl)

116.0 [96.0–139.0]

Apolipoprotein AI (mg/dl)

152.0 [134.0–171.0]

Apolipoprotein B (mg/dl)

90.0 [75.0–107.0]

Glycated hemoglobin - HbA1c (%)

5.40 [5.10–5.70]

HOMA-IR index (10–6 mol∙U∙l−2)

2.31 [1.42–4.03]

Insulin sensitivity OGTT (1019 l2∙mol−2)

10.65 [6.33–17.38]

ISIclamp (106 l∙kg−1∙min−1)***

0.074 [0.051–0.111]

C-peptide 30’(pmol/l)

1889 [1434–2489]

IGI [(Ins30′-Ins0′)/(Glc30′-Glc0′)]

140.7 [86.3–226.6]

AUC C-Pep ′0−30′/AUC Glc0′−30′

184.6 [143.6–239.1]

AUC C-Pep 0′−120′/ AUC Glc0′−120′

298.8 [242.9–364.7]

  1. *Available in 339 subjects; **available in 455 subjects; ***available in 498 subjects.
  2. Data are given as counts or medians [interquartile range]. BMI, body mass index; BW, body weight; OGTT, oral glucose tolerance test; HOMA-IR, homeostasis model assessment of insulin resistance; ISI, insulin sensitivity index; IGI, insulinogenic index; Ins, insulin; C-Pep, C-peptide; Glc, glucose; AUC, Area Under the Curve.