Table 4 Cause-specific risk models for ESKD and death before ESKD in high-risk participants.

From: Long-term risk for end-stage kidney disease and death in a large population-based cohort

 

Obese

Hypertensive

Diabetic

ESKD

Death before ESKD

ESKD

Death before ESKD

ESKD

Death before ESKD

Risk Factor

HR

HR

HR

HR

HR

HR

 

(95% CI)

(95% CI)

(95% CI)

(95% CI)

(95% CI)

(95% CI)

Cases / n

83/20,137

3,347/20,137

271/65,555

13,532/65,555

78/6,219

2,028/6,168

Smoking status [smokers vs. non-smokers]

1.27

1.25

1.44

1.36

1.71

1.25

 

(0.79–2.03)

(1.15–1.36)

(1.11–1.87)

(1.34–1.45)

(1.05–2.78)

(1.13–1.39)

BMI [kg/m2]

1.04

1.04

0.99

1.00

1.02

1.00

 

(0.98–1.10)

(1.03–1.05)

(0.96–1.02)

(0.99–1.00)

(0.97–1.06)

(0.99–1.01)

Fasting blood glucose [mmol/L]

1.27

1.05

1.19

1.06

1.16

1.05

 

(1.20–1.34)

(1.04–1.07)

(1.14–1.23)

(1.06–1.07)

(1.10–1.23)

(1.03–1.06)

Systolic blood pressure [5 mmHg]

1.03

1.02

1.11

1.02

1.09

1.01

 

(0.96–1.10)

(1.01–1.03)

(1.07–1.15)

(1.02–1.03)

(1.03–1.17)

(1.00–1.02)

Diastolic blood pressure [5 mmHg]

1.18

0.99

1.06

1.00

1.06

1.01

 

(1.05–1.32)

(0.98–1.01)

(1.00–1.13)

(0.99–1.01)

(0.95–1.19)

(0.99–1.03)

Log_triglycerides [mmol/L]

1.40

1.07

1.63

1.09

1.29

1.09

 

(0.93–2.11)

(0.99–1.15)

(1.30–2.05)

(1.05–1.13)

(0.87–1.92)

(1.00–1.19)

Total cholesterol [mmol/L]

1.33

1.00

1.18

0.96

1.19

0.99

 

(1.16–1.51)

(0.97–1.03)

(1.08–1.29)

(0.95–0.98)

(1.05–1.36)

(0.95–1.02)

Log_GGT [U/L]

0.74

1.36

0.94

1.33

1.00

1.25

 

(0.53–1.05)

(1.29–1.43)

(0.79–1.13)

(1.30–1.36)

(0.74–1.36)

(1.18–1.32)

  1. Continuous data were used. All models are fully adjusted. The HR corresponds to a unit change in the quantity in square brackets.
  2. Abbreviations: ESKD, end-stage kidney disease; GGT, γ-glutamyltransferase.