Table 3 Visual field progression of retinitis pigmentosa patients in the subgroups of variables.

Variable	n	Coefficient	95% CI	P value	P for interaction
MD
Sex (men)	41	−0.47	−0.69 to −0.26	<0.0001	0.12
Sex (women)	77	−0.48	−0.60 to −0.35	<0.0001	0.12
MS
Sex (men)	41	−0.64	−0.94 to −0.34	<0.0001	0.66
Sex (women)	77	−0.56	−0.74 to −0.38	<0.0001	0.66
FS
Sex (men)	41	−0.62	−0.92 to −0.33	<0.0001	0.53
Sex (women)	77	−0.52	−0.69 to −0.34	<0.0001	0.53
MD
Age, ≤ 46 (years)	57	−0.49	−0.63 to −0.35	<0.0001	0.72
Age, > 46 (years)	61	−0.45	−0.60 to −0.30	<0.0001	0.72
MS
Age, ≤ 46 (years)	57	−0.48	−0.67 to −0.29	<0.0001	0.18
Age, > 46 (years)	61	−0.68	−0.92 to −0.45	<0.0001	0.18
FS
Age, ≤ 46 (years)	57	−0.47	−0.67 to −0.26	<0.0001	0.32
Age, > 46 (years)	61	−0.62	−0.83 to −0.40	<0.0001	0.32
MD
AD	20	−0.44	−0.69 to −0.18	0.002	0.75
AR + Sporadic	98	−0.52	−0.93 to −0.10	<0.0001	0.75
MS
AD	20	−0.64	−0.94 to −0.35	0.0002	0.73
AR + Sporadic	98	−0.57	−0.74 to −0.40	<0.0001	0.73
FS
AD	20	−0.66	−0.95 to −0.37	0.0001	0.51
AR + Sporadic	98	−0.52	−0.69 to −0.36	<0.0001	0.51
MD
CST, > 252	59	−0.47	−0.62 to −0.32	<0.0001	0.81
CST, ≤ 252	59	−0.49	−0.64 to −0.34	<0.0001	0.81
MS
CST, > 252	59	−0.39	−0.53 to −0.25	<0.0001	0.01
CST, ≤ 252	59	−0.78	−1.04 to −0.52	<0.0001	0.01
FS
CST, > 252	59	−0.30	−0.43 to −0.17	<0.0001	0.001
CST, ≤ 252	59	−0.79	−1.04 to −0.54	<0.0001	0.001

Average progression rate of MD, MS, and FS using linear mixed models in the subgroups of variables. The patients were divided into two groups by median baseline age and CST. Random intercepts and random slopes for each subject are adopted for analysis. The coefficient of time (years) of each model is the fixed effect of the slopes, or the average progression rate.
CI, confidence interval.

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