Table 2 The estimated changes in miR-222 and miR-46a associated with screen time, BMI and physical activity as evaluated in separate models.

From: Children’s screen time alters the expression of saliva extracellular miR-222 and miR-146a

 

Effect size (95% CI)*

p-value

miR-222

Total screen time

3.44 (1.34–5.58)

0.0016

BMI, continuous

−2.20 (−8.07–4.04)

0.48

BMI, categorical

 

0.59

 Underweight

18.51 (−18.57–72.46)

 

 Normal weight

Ref

 

 Overweight

13.26 (−25.97–73.30)

 

Physical activity

 

0.74

 None

Ref

 

 Low

10.19 (−35.15–87.24)

 

 Middle

−2.74 (−44.31–69.82)

 

 High

−12.75 (−51.85–58.09)

 

miR-146a

Total screen time

1.84 (−0.04–3.75)

0.055

BMI, continuous

−4.08 (−8.75–0.84)

0.10

BMI, categorical

 

0.43

 Underweight

12.74 (−16.88–52.90)

 

 Normal weight

Ref

 

 Overweight

−15.35 (−40.23–19.90)

 

Physical activity

 

0.71

 None

Ref

 

 Low

27.67 (−17.99–98.79)

 

 Middle

15.97 (−28.12–87.07)

 

 High

19.81 (−27.22–97.24)

 
  1. *Effect sizes represent the mean% change with the 95% confidence intervals in miRNA for a 1-hour increment in weekly screen time/1 kg/m² increase in BMI or compared to a reference group. Models were adjusted for gender, age, passive smoking exposure, maternal education and RNA content of the extracellular fraction.
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