Figure 5 | Scientific Reports

Figure 5

From: Distinctiveness in virological features and pathogenic potentials of subgenotypes D1, D2, D3 and D5 of Hepatitis B virus

Figure 5

Efficacy of different HBV/D-subgenotype in induction of tumorigenesis. Relative expression of (A) N-cadherin, (B) E-cadherin and (C) Vimentin as determined by real-time PCR in D1, D2, D3 and D5 transfected Huh7 cells. (D) Cellular proliferation capabilities were measured by MTT assay in different HBV/D-subgenotype transfected Huh7 cells. (E) Cellular migration of transfected Huh7 cells was evaluated by wound healing assay. Representative field (x100) shows wound healing for D1, D2, D3 and D5 transfected Huh7 cells at 48 hrs of scratching. The graph shows the percentage of wound healing area determined by ImageJ software (mean ± SD, n = 3). Paired t-test p values; *p < 0.05, **p < 0.01, ***p < 0.001.

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