Figure 3
From: Transcriptomic response of breast cancer cells to anacardic acid
AnAc downregulated genes canonical pathway map for MCF-7 cells generated by MetaCore. Networks identified were: 1) SCD, LXRα, Insulin, Norepinephrine, IGF-1; 2) miR-22, CDIP; 3)MALL, NCOA2, E2 cytoplasm, hyaluronic acid extracellular, ESR1 (nuclear); 4) MRLC, CaMK II, STIM1, CARACM1, Ca; 5) uPAR, fibrinogen, BDKRB2, C2b, alpha-X/beta-2 integrin. All objects with the blue circle are downregulated by AnAc. The lines are connections that have been documented in the literature with green lines indicating canonical pathways.
