Table 1 Data of optical coherence tomography angiography (OCT-A) parameters measured in control subjects versus CADASIL patients.

From: OCT-Angiography reveals reduced vessel density in the deep retinal plexus of CADASIL patients

Variables

Controls (n = 21)

CADASIL (n = 21)

p-value

Macular parameters

FAZs [mm2]

0.30 ± 0.11

0.27 ± 0.11

0.27

FAZd [mm2]

0.40 ± 0.14

0.35 ± 0.11

0.30

VDsM [%]

53.76 ± 4.87

53.25 ± 2.10

0.06

VDdM [%]

61.33 ± 1.93

57.62 ± 2.46

<0.0001

Optic nerve head parameters

VDrID [%]

48.02 ± 9.41

45.54 ± 11.04

0.44

VDrPP [%]

64.01 ± 3.63

63.58 ± 1.93

0.84

VDnhID [%]

56.23 ± 4.73

52.61 ± 9.71

0.27

VDnhPP [%]

63.29 ± 2.34

63.86 ± 1.79

0.69

ODa [µm]

132.10 ± 16.16

141.80 ± 14.52

0.07

IDa [µm]

103.30 ± 13.96

108.50 ± 13.77

0.31

VWa [µm]

14.37 ± 2.75

16.65 ± 2.04

0.01

ODv [µm]

165.30 ± 13.73

167.00 ± 16.44

0.64

IDv [µm]

137.60 ± 14.58

140.50 ± 15.47

0.34

VWv [µm]

13.86 ± 2.63

13.29 ± 3.05

0.42

Choriocapillaris [CC] parameters

CC decorrelation index [%]

103.30 ± 3.50

102.30 ± 3.67

0.26

Flow area [%]

45.16 ± 1.24

45.17 ± 1.25

0.96

FV10000 [µm2]

0.70 ± 0.04

0.65 ± 0.06

0.04

FV 40000 [µm2]

0.39 ± 0.07

0.35 ± 0.08

0.14

  1. Foveal avascular zone of superficial retinal plexus (FAZs), FAZ of deep retinal plexus (FAZd), vessel density (VD) in superficial plexus of parafoveal region of central macula (VDsM), VD in deep plexus of parafoveal region of central macula (VDdM), VD in the radial peripapillary capillary layer of disc region (VDrID), VD in the nerve head layer of disc region (VDnhID), VD in the radial peripapillary capillary layer of peripapillary region (VDrPP), VD in the nerve head layer of peripapillary region (VDnhPP), outer diameter of artery (Oda), inner diameter of artery (Ida), arterial vessel wall (VWa), outer diameter of vein (ODv), inner diameter of vein (IDv), venous vessel wall (VWv), choriocapillaris (CC) decorrelation index, flow area, flow void area larger than 10,000 µm2 (FV10000), flow void area larger than 40,000 µm2 (FV40000).