Table 1 Descriptive parameters of faecal functional metagenomics networks (FMNs).

From: Combining amplicon sequencing and metabolomics in cirrhotic patients highlights distinctive microbiota features involved in bacterial translocation, systemic inflammation and hepatic encephalopathy

Parameter

FMN Controls (n = 14)

FMN Cirrhotic Patients (n = 35)

Nodes

63

62

Edges

263

112

Synergistic interactions (%)

223 (84.8)

88 (78.6)

Competitive interactions (%)

40 (15.2)

24 (21.4)

Syn/Com ratio

5.58

3.67

Density

0.135

0.059

Modularity

0.589

0.401

Keystone species (BC, FMC, [Otu], Rel.abund.%)

G. formicilis (442.4, I, [33], 2.23)

O. ruminantium (289.4, II, [26], 2.95)

F. prausnitzii (231.1, V, [9], 5.47)

A. onderdonkii (204.8, II, [42], 0.72)

R. faecis (194.9, III, [22], 1.73)

B. vulgatus (277.1, I, [1], 16.98)

B. stercoris (264.7, II, [29], 1.18)

F. prausnitzii (209.6, II, [9], 1.76)

V. dispar (174.4, I, [7], 9.68)

B. uniformis (171.2, I, [8], 2.06)

Keystone metabolites (BC, FMC)

acetate (279.3, II)

serine (162.0, IV)

β-arabinose (158.3, V)

lysine (147.4, III)

histidine (121.7, V)

threonine (332.5, I)

n-butyrate (256.2, II)

histidine (242.9, II)

methanol (197.7, II)

proline (176.8, II)

  1. BC = betweenness centrality value.
  2. FMC = functional metagenomics community (in Roman numbers).
  3. Otu = operational Taxonomical Unit.
  4. Rel.abund. = relative abundance (%).
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