Table 3 Microbiota features related to hepatic encephalopathy (HE) in cirrhotic patients.

From: Combining amplicon sequencing and metabolomics in cirrhotic patients highlights distinctive microbiota features involved in bacterial translocation, systemic inflammation and hepatic encephalopathy

Species, KOrths, Metabolites

Logistic Reg. Coeff.

Odds Ratio (OR)

Randomized Lasso Coeff. (RLC)

Elastic Net Coeff. (ENC)

SGDC Coeff.

Peripheral blood

Clostridium indolis

−0.151

0.90

0.530

−0.049

−0.316

Methylobacterium extorquens

1.275

2.42

0.445

0.042

0.642

Stenotrophomonas pavanii

1.231

2.35

0.555

0.082

0.665

K07147

0.450

1.37

0.205

0.033

0.562

IL6

0.355

1.28

0.800

0.057

0.319

Faeces

Bacteroides coprocola

1.210

2.31

0.745

0.051

0.738

Bacteroides coprophilus

−0.609

0.66

0.890

−0.005

−0.371

Bacteroides faecis

−0.804

0.57

0.785

−0.033

−0.465

Bifidobacterium longum

1.092

2.13

0.790

0.096

0.728

K00382

0.466

1.38

0.305

0.046

0.729

K11741

0.446

1.36

0.190

0.020

0.695

K03111

0.540

1.45

0.175

0.023

0.664

K03832

−0.496

0.71

0.100

−0.012

−0.663

methanol

0.772

1.71

0.260

0.136

0.697

threonine

0.466

1.38

0.005

0.007

0.500

n-butyrate

−0.371

0.77

0.005

−0.018

−0.340

  1. K07147: methionine sulfoxide reductase catalytic subunit msrP [EC:1.8.-.-].
  2. K00382: dihydrolipoamide dehydrogenase pdhD [EC:1.8.1.4].
  3. K11741: quaternary ammonium compound-resistance protein sugE.
  4. K03111: single-strand DNA-binding protein ssb.
  5. K03832: periplasmic protein tonB.
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