Figure 1

Change in mean brachial ankle pulse wave velocity (baPWV) over the 6-year follow-up period according to severity of obstructive sleep apnoea (OSA) in participants without hypertension (n = 1242). P-values were derived from multivariate mixed-effect linear regression models adjusting for age, sex, smoking, alcohol status, mean arterial pressure, body mass index (BMI), fasting glucose, high-density lipoprotein (HDL) cholesterol, diabetes mellitus (DM) medication at baseline and change in BMI at the 6-year follow-up. Ptime and Posa indicate the effect of time on change in baPWV over 6 years and the effect of OSA groups on baPWV across time, respectively; Pinteraction indicates whether the change in baPWV over time differs significantly among OSA groups. *Adjusted mean baPWV in the moderate-to-severe OSA group is significantly different from that in the non-OSA group, according to pairwise comparisons.