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Figure 1

From: Lycium barbarum polysaccharide encapsulated Poly lactic-co-glycolic acid Nanofibers: cost effective herbal medicine for potential application in peripheral nerve tissue engineering

Figure 1

Schematic illustration of the preparation process and working hypothesis for coaxial electrospun fiber scaffolds. (a) The setup of coaxial electrospinning: the spinneret is composed of two concentric needles; the outer needle is used to deliver the shell solution (blue), while the inner needle is used to eject the core solution (Pink). (b) The LBP encapsulated in the core of coaxial fibers could be released in a sustained manner to promote differentiation of PC12 cells with Differentiation Medium+NGF. (c) Scaffolds coated with Poly-L-lysine could promote the adhesion of Schwann cells, and the released LBP could enhance the myelination of Schwann cells. (d) The neurite outgrowth of DRG neurons might be improved under the synergistic effect of LBP and NGF.

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