Figure 2
From: Control of Spreading Depression with Electrical Fields
Examples of modulation experiments. (a) Electric field effects (116 mV/mm) on the propagation and invasion of SD into the various layers of coronal slices imaged via IOS. Normal SD propagation through all cortical layers during a control trial (left). SD propagation under applied surface-negative DC field confines the spread to the superficial cortical layers (middle), while SD propagation was forced into the deeper layers of cortex and arrested by applied surface-positive DC field (right). (b) Corresponding timing of SD signal as a function of cortical depth and time, the color bar representing light intensity changes as percent of baseline for the line of pixels indicated in red in upper plots (lower row in (a)). Note that the pixel cross-section for the positive field trial was taken nearer to the injection area due to the spatial arrest of SD.
