Figure 5
Hypoxic cell distribution determine vascular network. Evolution of a vascular system with an initial capillary at the bottom and uniformly distributed hypoxic cells (green dots), sources of VEGF which drive the chemotactic response by ECs (maximum proliferation 2.8 × 10−4 s−1 and maximum tip cell velocity 0.375 μm/min). Four time points are represented. The bottom row shows the same network growth with the vessels with blood flow in red.
