Figure 8

Endogenous CYP24A1 induction in HL-60 cells by compounds in the presence of 3 nM Vitamin D₃: (a) VDR agonists: data expressed as percentage of vitamin D₃ alone (b) VDR antagonists: data are expressed as percentage of vitamin D₃ alone only for compounds exhibiting significant inhibition of at least p < 0.05.