Figure 2

Top hit interactors in the FET proteins and MATR3 interactomes. The top ranked (by total peptide number) proteins in each interactome are shown. The rank, HGNC official symbol, calculated molecular weight, best-known function, total and unique peptide counts are shown. Functions in splicing (pink), transcription (txn, orange), DNA damage response (green), neuronal (blue) and other (black) are indicated. The symbols of ALS-causative proteins are in red. The stars indicate U1 snRNP components.