Figure 3 | Scientific Reports

Figure 3

From: Protective effect of hydroxysafflor yellow A against acute kidney injury via the TLR4/NF-κB signaling pathway

Figure 3

HSYA preconditioning ameliorates tubular apoptosis induced by I/R. (A) Representative images (magnification, x400) of renal TUNEL assay from rats subjected to sham group, I/R + Vehicle group, and I/R + HSYA. (B) The percentage of TUNEL-positive cells in kidney sections increased following I/R and decreased following treatment with HSYA (*P < 0.05 vs. Sham; #P < 0.05 vs. I/R + Vehicle. n = 8 rats per group). (C) Anti-apoptotic effects on HK-2 cell following H/R injury were confirmed by Hoechst 33258 staining. Quantitative analysis of apoptosis is shown in (D). Data were presented as the means ± SD and were representative of three independent experiments; *P < 0.01 versus Control; #P < 0.01 versus H/R.

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