Table 1 Antibacterial activity of the peptides.

From: Exploring the role of unnatural amino acids in antimicrobial peptides

MIC (µM)a

Peptide

Gram-negative

Gram-positive

 

E. coli

ATCC25922

P. aeruginosa

ATCC27853

PAO1

Wt

B. spizizenii

ATCC6633

S. aureus

MRSA

S. aureus

ATCC6538P

(P)GKY20

10

20

20

20

80

5

P9Nal(SS)

10

2.5

10

10

20

10

P9Trp(SS)

10

2.5

10

40

40

20

P9Nal(SR)

10

1.25

10

40

40

40

  1. aMIC is the minimum inhibitory concentration leading to no visible bacterial growth. Assays were carried out three times as independent experiments.
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