Table 1 Time-course of serum cytokine levels in mice chronically infected with Mycobacterium lepraemurium.

From: Chronic infection with Mycobacterium lepraemurium induces alterations in the hippocampus associated with memory loss

Cytokine

Lower limit of detection(pg/mL)

 

Days infections MLM

Statistical post hoc analysis

Controls

40

80

120

Cont vs 40

Cont vs 80

80 vs 120

IL-2

5

ND

ND

ND

ND

IL-12

1

7.71 ± 0.78

5.05 ± 0.65

8.44 ± 2.00

14.47 ± 0.20

*

INF-γ

20

ND

ND

ND

ND

IL-4

10

ND

ND

49.05 ± 11.17

73.99 ± 3.75

***

IL-5

15

ND

ND

ND

ND

IL-10

15

ND

ND

ND

ND

  1. Quantification of cytokines in sera of control and MLM-infected mice. Values are presented as mean ± SEM. Two-way ANOVA test, post hoc Tukey multiple comparisons test. *p < 0.05; **p < 0.01 and ***p < 0.001 as compared to control group. IL- = interleukin; ND = no-detectable; IFN = interferon; MLM = Mycobacterium lepraemurium.