Figure 1

Expression of BRAFV600E and KRASG12V resulted in cytoskeletal rearrangement and Mucin production. CaCO2-control, CaCO2-BRAFV600E and CaCO2-KRASG12V cells cultivated with 1.0 g/L glucose were supplemented with Doxycycline for 16 days. Vacuoles containing Mucin are depicted by arrows. Pictures were taken with Zeiss Axio Z1 microscope using 200x magnification.