Table 1 Gene set enrichment analysis of differentially expressed genes in SUM149 cells cultured in Matrigel compared to monolayer using gene sets clinically relevant to TNBC.

From: CSF-1/CSF-1R axis is associated with epithelial/mesenchymal hybrid phenotype in epithelial-like inflammatory breast cancer

Gene set

Number of genes

Efron-Tibshirani’s GSA test p value

Direction of overexpression

EMT

14

<0.001

Matrigel

IKS

15

0.466

Matrigel

MKS

12

0.397

Matrigel

CL

19

0.096

Monolayer

GGI

128

0.21

Monolayer