Figure 1
From: Modified Newcastle Disease virus as an improved vaccine vector against Simian Immunodeficiency virus

Construction of the modified recombinant NDVs expressing SIV gp160 gene. The SIV gp160 ORF of SIV mac 239 was inserted between P and M genes in the rNDV vectors. Genes derived from rBC or AKO-18 are shown as black or gray rectangles, respectively. F gene segments derived from the NDV strain LaSota strain are shown as white bars. All the viruses contain the avirulent F protein cleavage site sequence of strain LaSota, or APMV-2 or APMV-8.