Table 2 Distribution of small intestinal mast cells.

	Mast cells/field (All fields)	Mast cells/field (GALT fields)	Mast cells/field (Other fields)	Mast cells/field (Skin)
Wild type	0.07 ± 0.03	0.35 ± 0.28	0.04 ± 0.02	11.5 ± 0.8
Kcnn4 ^−/−	0.10 ± 0.04	0.16 ± 0.12	0.10 ± 0.05	12.3 ± 2.0
Cftr ^{ΔF508/ΔF508}	0.41 ± 0.18^a	1.46 ± 0.04^b,c	0.14 ± 0.05	12.2 ± 1.2
Cftr^{ΔF508/ΔF508}/Kcnn4^−/−	0.18 ± 0.03	0.40 ± 0.19	0.15 ± 0.05	12.1 ± 0.4
Cftr^fl/fl/Villin^Cre/−	0.06 ± 0.02	0.20 ± 0.05	0.04 ± 0.02	± 0.5
Wild type	0.08 ± 0.04	0.40 ± 0.30	0.03 ± 0.02	13.2 ± 3.0
Stat6 ^−/−	0.08 ± 0.03	0.18 ± 0.09	0.04 ± 0.01	12.0 ± 2.0
Cftr ^{ΔF508/ΔF508}	0.26 ± 0.07^d	1.20 ± 0.32^e	0.10 ± 0.06	13.8 ± 0.8
Cftr^{ΔF508/ΔF508}/Stat6^−/−	0.19 ± 0.08	0.69 ± 0.29	0.06 ± 0.02	13.6 ± 1.8

GALT: Gut associated lymphoid tissue.
Values are given as mean ± S.E.M. Unpaired Student’s test.
^aIndicates p = 0.008,
^bp = 0.032,
^dp = 0.032 and
^ep = 0.032 vs corresponding wild type group.
^cIndicates p = 0.032 vs Cftr^{ΔF508/ΔF508}/Kcnn4^−/−; 80 to 120 400x optical fields per animal were analysed and n = 4–5 animals per group were used.

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