Figure 4 | Scientific Reports

Figure 4

From: Damage-associated molecular pattern recognition is required for induction of retinal neuroprotective pathways in a sex-dependent manner

Figure 4

Microglia phenotype following light damage. Mice were exposed to light damage (LD). Eight hours following LD, flat mounts were made as described in methods, and stained with IBA1. (A) The proportion of microglia different activation states was calculated and plotted. (B) Microglia were counted from four consistent positions adjacent to the optic nerve, and sorted into categories, depending on their shape by a masked observer. n = 14 (No LD), and n = 4–7 mice exposed to light damage, combined from two independent experiments. Number of mice in specific groups is shown in the figure. Statistics: Two-way ANOVA with SIDAK post hoc test. The scale bar shown in (B) is 50 µm.

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