Figure 2 | Scientific Reports

Figure 2

From: Further dissection of QTLs for salt-induced stroke and identification of candidate genes in the stroke-prone spontaneously hypertensive rat

Figure 2

Genomic composition of the subcongenic strains. Congenic regions (homozygous for SHR alleles) of subcongenic strains are shown as closed columns. Vertical bars indicate regions including a recombination. Light grey boxes indicate the haplotype blocks that differed between SHRSP and SHR (see ref.6). A dark grey box indicates the region narrowed down through the current analysis of subcongenic strains (see Results). Note that ‘SHRSPrch’ was omitted from the names of the subcongenic lines. ‘SHRSPrch1.’ and ‘SHRSPrch18.’ mean Chr-1 and −18 subcongenic strains, respectively. The numbers following period, e.g., 31 in the SHRSPrch1.31, are the identification number for each subconogenic strain. Averages of systolic blood pressure (SBP) and relative risk of stroke are shown under the columns representing the subcongenic strains (see Table S1 and Fig. 3 for the details). *P < 0.05 vs. SHRSP by Dunnet’s post-hoc test. #P < 0.05 by the Cox hazard model.

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