Figure 2
Adult multipotent mesenchymal stromal cells (MSC) exhibit CD271-positive subpopulation. (a) Representative dot plots of CD271 expression by adult and fetal MSC and of human skin fibroblast (HSF). (b) CD271 surface marker expression and (c) gene expression, both normalized to stromal non-stem control (HSF). Mean and standard deviation for single MSC types (n = 3) or for adult (n = 6) vs. fetal (n = 12) MSC groups (separated by dotted line). Statistical analysis was by non-parametric two-tailed Mann-Whitney-Wilcoxon test (P = 0.0004) or by Kolmogorov-Smirnov normality test (α = 0.05), followed by unpaired two-tailed t-test (P = 0.012); **P < 0.01, ***P < 0.001. ADMSC, adipose tissue MSC; BMMSC, bone marrow MSC; CBMSC, cord blood MSC; WJMSC, Wharton’s jelly MSC; PVC, perivascular cell; AFC, amniotic fluid cell; adult, MSC from adult sources (black bar); fetal, MSC from fetal sources (white bar).
