Figure 1
From: Muscarinic receptor-induced contractions of the detrusor are impaired in TRPC4 deficient mice
(A,B) Representative tension recordings of spontaneous activity in detrusor strips taken from wild-type (A) and TRPC4−/− mice (B). (C,D) Summary bar charts showing mean amplitude (C) and frequency (D) of spontaneous detrusor contractions in wild-type (WT, open bars) and TRPC4−/− mice (filled bars). (E,F) Representative KCl (60 mM)-evoked contractions in wild-type (E) and TRPC4−/− (F) detrusor strips. (G) Summary bar chart plotting mean KCl-evoked contraction amplitude, (measured as area under curve, mN.s) in wild-type (WT, open bars) and TRPC4−/− detrusor strips. Error bars represent SEM. **** denotes p < 0.0001.
