Figure 5
From: Muscarinic receptor-induced contractions of the detrusor are impaired in TRPC4 deficient mice
(A,B) Representative neostigmine (1 μM)-induced contraction of wild-type (A) and TRPC4−/− detrusor strips (B). Solid red lines in A&B represent single exponential fits (τ). (C,D) Summary bar charts showing mean amplitude of neostigmine-evoked contractions (C) and rate of contraction (1/τ) (D) in wild-type (WT, open bars) and TRPC4−/− preparations (filled bars). Error bars represent SEM. ** denotes p < 0.01 and ****p < 0.0001, respectively.
