Figure 3 | Scientific Reports

Figure 3

From: MicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium

Figure 3

Validation of several predicted miRNA targets. Based on qRT-PCR, Adrb2 mRNA, but not Ppp3r1 and Cask mRNAs, was significantly downregulated by hypercholesterolemia in the heart compared to the control group (A). *p < 0.05 vs. Control (Student’s t-test). n = 6/group. Calcineurin B type 1 (CNB1) translated from Ppp3r1 mRNA was significantly downregulated in the hypercholesterolemic myocardium compared to the control group (B). *p < 0.05 vs. Control (Student’s t-test). n = 8–9/group. Western blot images are only representative.

Back to article page