Figure 7
Inhibitory effect of Nintedanib treatment on the protein expression of pro-angiogenic molecules in tumor tissues is dependent on tumor stage. Comparative outcomes of Human Angiogenesis Proteome Profiler™ Array analysis of PC3 tumor xenograft tissues from both Experiment 1 and Experiment 2 studies. Images represent the protein blot profile of representative tumor sample lysates (2 dot lanes per molecule). Molecules showing difference in densitometric values between vehicle control and Nintedanib groups are marked by a circle. Fold changes of down regulated molecules (red arrow) and upregulated molecules (blue arrow) are listed for both studies.
