Figure 6
Treatment of HSD rats with Activator-3 improves metabolic health. (A–D) OGTT analysis of control and HSD rats on zero day (A and B) and 30 days (C and D). (E–H) Analysis of cholesterol (E), triglyceride (F) free fatty acid (G) and body weight (H) of control and HSD fed rats. Statistical analysis were performed using one way ANOVA followed by tukey’s post-hoc test. *p < 0.05, **p < 0.01, ***p < 0.001. (I,J). Western blot analysis of pAMPK, AMPK, pACC, ACC and β-actin of the soleus muscle tissue of normal, HSD fed rats treated with vehicle control or 10 mg/kg /day Activator-3 for 30 days.
