Figure 3
Bioinformatic analysis of the proteins increased or exclusively expressed in cells grown on ns-ZrOx in comparison to flat-ZrO2. (A) The proteins listed in Table S3 were classified into different biological processes according to the Gene Ontology classification system GO-biological process (GOBP), GO-cellular component (GOCC) and GO-molecular function (GOMF) using Panther software. Functional grouping was based on p value ≤ 0.05. The numbers in the bars indicate the number of genes for each category. (B) Reactome analysis. Only categories with confidence level: Very High (K value 0.75–1) (Dark Purple) and High (K value 0.5–0.75) (Purple) are reported. (C) Network interactions in the same proteins data set were analyzed by String. Active interactions: text mining, experiments, databases; edges thickness indicates “confidence”. The proteins are indicated by the official gene symbol.
