Table 1 Adipogenesis-related genes including Pparg and Cebpa were suppressed in Hmgb2−/− MSCs.

From: HMGB2 is a novel adipogenic factor that regulates ectopic fat infiltration in skeletal muscles

Gene symbol

Hmgb2−/− 1

Hmgb2−/− 2

WT 1

WT 2

ave (Hmgb2−/−)/ave (WT)

Hmgb2

32.8

52.4

1,406.4

2,398.2

0.02

Lpl

26.8

30.4

1,218.0

888.2

0.03

Fabp4

65.1

135.9

435.2

1,033.7

0.14

Pparg

214.1

231.4

869.7

487.9

0.33

Ebf1

114.9

43.6

269.4

119.1

0.41

Lifr

54.6

82.3

218.3

112.7

0.41

Ppargc1a

33.9

34.1

110.7

46.4

0.43

Cebpa

40.6

38.3

70.4

96.9

0.47

  1. The list of genes whose expression levels were less than half in Hmgb2−/− MSCs compared to in WT MSCs.