Table 1 Baseline characteristics, vital signs and symptoms of AHF patients with worsening of CHF vs. de novo AHF patients.

From: Acute Heart Failure developed as worsening of Chronic Heart Failure is associated with increased mortality compared to de novo cases

 

All AHF patients

(N = 152)

De novo AHF

(N = 47)

Worsening of CHF

(N = 105)

p-value

Age (years)

77.3 (45.5–96.7)

75.7 (45.5–93.0)

77.5 (50.6–96.7)

0.312

Female

79 (52.0%)

20 (42.6%)

59 (56.2%)

0.160

BMI (kg/m2)

28.5 (16.3–43.5)

30.1 (16.3–38.6)

27.7 (17.1–43.5)

0.113

Weight (kg)

80.0 (40.0–144.0)

89.0 (50.0–125.0)

79.0 (40.0–144.0)

0.042

Smoking

38 (25.0%)

15 (31.9%)

23 (21.9%)

0.225

NYHA class

   

0.124

2

11 (7.2%)

6 (12.8%)

5 (4.8%)

 

3

83 (54.6%)

27 (57.4%)

56 (53.3%)

 

4

58 (38.2%)

14 (29.8%)

44 (41.9%)

 

MAP (mmHg)

103.3 (53.3–160.0)

110.0 (70.0–160.0)

100.0 (53.3–156.7)

0.007

Heart rate (beats/min)

100.0 (36.0–160.0)

110.0 (36.0–160.0)

99.0 (50.0–150.0)

0.041

JVD

52 (34.2%)

10 (21.3%)

42 (40.0%)

0.027

Enlarged liver

53 (34.9%)

9 (19.1%)

44 (41.9%)

0.009

Peripheral edema

105 (69.1%)

26 (55.3%)

79 (75.2%)

0.022

Ascites

21 (13.8%)

4 (8.5%)

17 (16.2%)

0.309

EF (%)

45.0 (20.0–70.0)

45.0 (20.0–65.0)

41.0 (20.0–70.0)

0.677

SPAP (mmHg)

45.0 (35.0–80.0)

40.0 (35.0–60.0)

47.5 (35.0–80.0)

0.002

  1. Data are presented as n (%) or as median and range (minimum to maximum). Differences between AHF patients with worsening of CHF and de novo AHF patients were tested with Fisher’s exact test or the Mann-Whitney U test, respectively.
  2. AHF, acute heart failure; BMI, body mass index; CHF, chronic heart failure; EF, ejection fraction; JVD, jugular venous distension; MAP, mean arterial pressure; NYHA, New York Heart Association functional classification; SPAP, systolic pulmonary artery pressure.
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