Figure 5 | Scientific Reports

Figure 5

From: Mechanistic insights into the augmented effect of bone marrow mesenchymal stem cells and thiazolidinediones in streptozotocin-nicotinamide induced diabetic rats

Figure 5

Effects of MSCs, PIO and their combination on oxidative stress and inflammatory markers in heart of diabetic rats. Cardiac MDA level (A), TOC (B), TAC (C), and MPO activity (D). All the experiments were repeated in 2 times and all data are presented as Mean ± SEM (n = 6–8 animals per group). *P < 0.05 vs. control; a P < 0.05 vs. diabetic group; b P < 0.05 vs. Diabetic + MSCs group. E & F represent Western blotting assay and quantitative analysis of iNOS and NFkB protein expressions in heart tissue of experimental animals. Expression of β actin was used to document equal protein loading. Data are expressed as fold change (relative to control group) WB was repeated in 2 times and all data are presented as Mean ± SEM (n = 3 animals per group). *P < 0.05 vs. control; a P < 0.05 vs. diabetic group; b P < 0.05 vs. Diabetic + MSCs group; c P < 0.05 vs. Diabetic + PIO group.

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