Table 1 Patient characteristics.

From: Downregulation of WNT11 is associated with bladder tissue fibrosis in patients with interstitial cystitis/bladder pain syndrome without Hunner lesion

 

Total (n = 30)

NHIC (n = 7)

HIC (n = 18)

p-value

Age (years)

59.7 ± 10.9

65.4 ± 7.3

56.5 ± 11.8

0.064

Gender (M/F)

4 vs 26

1 vs 6

2 vs 16

0.929

Duration of symptoms (months)

39.6 ± 31.9

70.8 ± 42.9

30.9 ± 22.8

0.046

PUF

22.6 ± 6.4

19.8 ± 4.0

23.7 ± 6.9

0.135

IC-Q

28.3 ± 7.0

25.0 ± 4.6

29.6 ± 7.5

0.051

VAS

6.9 ± 2.4

6.8 ± 1.7

7.0 ± 2.7

0.959

Voiding diary

   Urinary frequency (times/day)

13.3 ± 6.9

8.5 ± 2.6

16.1 ± 7.3

0.006

   Urinary urgency (times/day)

9.5 ± 7.7

7.0 ± 3.5

10.9 ± 9.5

0.682

   Urge incontinence (times/day)

0.6 ± 1.4

1.1 ± 1.6

0.4 ± 1.3

0.213

   Maximum bladder capacity (ml)

262.6 ± 160.6

361.4 ± 133.6

208.6 ± 163.9

0.006

  1. Standard abbreviations: EMT, epithelial-mesenchymal transition; GAG, Glycosaminoglycans; HIC, Hunner-type IC; IC/BPS, interstitial cystitis/bladder pain syndrome; IC-Q, O’Leary-Sant Symptom and Problem Index; MSCs, mesenchymal stem cells; NAC, N-acetylcysteine; NHIC, non-Hunner-type IC; PUF, Pelvic Pain and Urgency/Frequency Patient Symptom Scale; RQ-PCR, Real-time quantitative reverse transcription polymerase chain reaction; SHH, sonic hedgehog; TUR-C, transurethral resection and coagulation; VAS, Visual Analogue Score.
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