Table 4 Descriptive statistics of parent-reported perceived efficacy of cannabis extracts.
From: Composition and Use of Cannabis Extracts for Childhood Epilepsy in the Australian Community
“Effective” cannabis extracts | “Ineffective” cannabis extracts | Total | |
---|---|---|---|
N (%) | N (%) | N (%) | |
38 | 13 | 51 | |
Adapted Patient Global Impression of Change (PGIC) scale | |||
1 Very much improved | 23 (61%) | — | 23 (45%) |
2 Much improved | 10 (26%) | — | 10 (20%) |
3 Minimally improved | 5 (13%) | — | 5 (10%) |
4 No change | — | 7 (54%) | 7 (13%) |
5 Minimally worse | — | 2 (15%) | 2 (4%) |
6 Much worse | — | 3 (23%) | 3 (6%) |
7 Very much worse | — | 1 (8%) | 1 (2%) |
Perceived change in seizure frequency | |||
75–100% reduction | 26 (68%) | — | 26 (51%) |
50–75% reduction | 5 (13%) | — | 5 (10%) |
25–50% reduction | — | — | — |
0–25% reduction | 2 (5%) | — | 2 (4%) |
No change | 1 (3%) | 9 (69%) | 10 (20%) |
Increase in seizures | — | 4 (31%) | 4 (7%) |
No rating: Emergency medication only | 2 (5%) | — | 2 (4%) |
No rating: Child experiencing infrequent seizures | 1 (3%) | — | 1 (2%) |
No rating: EEG activity improved but not seizures | 1 (3%) | — | 1 (2%) |
Reduction in child’s antiepileptic drug(s) after starting cannabis extracts | |||
Yes, all | 3 (8%) | — | 3 (6%) |
Some medication but not all | 22 (58%) | — | 22 (43%) |
No, none | 13 (34%) | 13 (100%) | 26 (51%) |