Table 4 Descriptive statistics of parent-reported perceived efficacy of cannabis extracts.

From: Composition and Use of Cannabis Extracts for Childhood Epilepsy in the Australian Community

 

“Effective” cannabis extracts

“Ineffective” cannabis extracts

Total

N (%)

N (%)

N (%)

38

13

51

Adapted Patient Global Impression of Change (PGIC) scale

  1 Very much improved

23 (61%)

23 (45%)

  2 Much improved

10 (26%)

10 (20%)

  3 Minimally improved

5 (13%)

5 (10%)

  4 No change

7 (54%)

7 (13%)

  5 Minimally worse

2 (15%)

2 (4%)

  6 Much worse

3 (23%)

3 (6%)

  7 Very much worse

1 (8%)

1 (2%)

Perceived change in seizure frequency

  75–100% reduction

26 (68%)

26 (51%)

  50–75% reduction

5 (13%)

5 (10%)

  25–50% reduction

  0–25% reduction

2 (5%)

2 (4%)

  No change

1 (3%)

9 (69%)

10 (20%)

  Increase in seizures

4 (31%)

4 (7%)

  No rating: Emergency medication only

2 (5%)

2 (4%)

  No rating: Child experiencing infrequent seizures

1 (3%)

1 (2%)

  No rating: EEG activity improved but not seizures

1 (3%)

1 (2%)

Reduction in child’s antiepileptic drug(s) after starting cannabis extracts

  Yes, all

3 (8%)

3 (6%)

  Some medication but not all

22 (58%)

22 (43%)

  No, none

13 (34%)

13 (100%)

26 (51%)

  1. Parent-rated perceived efficacy of 51 cannabis extracts on the adapted Patient Global Impression of Change (PGIC) scale of change in child’s overall condition, a rating of valid percentage change in seizure frequency, and changes to the child’s antiepileptic drug regimen after commencing cannabis extracts.