Figure 1
Critically ill patients demonstrate elevated BSP serum levels at admission to the ICU. (A) BSP serum levels at admission to the ICU were significantly elevated in patients with critical illness (n = 136) compared to healthy blood donors (n = 50). (B,C) BSP concentrations at admission to the ICU were further elevated in patients with more severe disease state according to initial APACHE-II scores (cut-offs are given in the figure). (D) Serum BSP concentrations were significantly correlated with the disease severity according to APACHE-II score in in critically ill patients. (E,F) Serum BSP levels in critically ill patients were independent on the presence of obesity (BMI > 30 kg/m2) or the presence of diabetes mellitus type 2. N values are given in the figures and tables; Spearman rank correlation test, correlation coefficient r, and P-values are given. *p < 0.05, **p < 0.01, ***p < 0.001.
