Figure 3
Development of BSP serum levels during the first 72 hours of treatment on the ICU. (A) Serum BSP concentrations demonstrated a slight decrease during the first 3 days of ICU treatment (Wilcoxon signed-rank test was used to assess the statistical difference between the repeated measurements in the same patient). (B) Serum BSP concentrations at d3 were compared between patients with different disease severities according to their respective APACHE-II-scores. (C) Serum BSP concentrations at day 3 were compared between patients with septic disease and patients with a non-septic disease etiology. (D) BSP serum concentrations after 3 days of ICU treatment were independent of the specific disease etiology. (E,F) Serum BSP levels after 3 days of ICU treatment were independent on the presence of obesity or diabetes mellitus type 2 in our cohort of patients. *p < 0.05.
