Figure 7
From: Intestinal permeability, digestive stability and oral bioavailability of dietary small RNAs
Uptake of SCR4 in aspirin-induced gut injury model. ICR mice were treated with oral dose of 200 mg/kg body weight aspirin (Aspirin) or PBS buffer (PBS) daily for 5 days before they were gavage fed FITC dextran-4000 FD4k and a single dose of 400 pmole of SCR4. (A) Gut permeability assayed by determining the concentration of FITC-dextran 4000 FD4K in the serum 4 h after gavage feeding of FD4K. (B) Serum SCR4 levels in mice was determined by qRT-PCR 1 h after gavage feeding of the sRNA. n = 5.
