Figure 5
From: A novel endoscopic classification for craniopharyngioma based on its origin

Histopathological examination of the origin and non-origin capsule of CPs. (A1-3) Relationship between origin site of Hypothalamic stalk CP and hypothalamus. (A1) Sagittal postcontrast T1-weighted MR image showing a typical Hypothalamic stalk CP which grows up to the third ventricle. (A2) Intraoperative photograph showing that the specimen was obtained from the junction of hypothalamus and stalk (white box), yellow dashed line indicates the board of hypothalamus. (A3) Histopathological examination (×200) of tissue in the white box (B) showing that tumor invades the hypothalamus with interdigitation or finger-like infiltration. (B1-3) Relationship between non-origin capsule of Suprasellar stalk CP and hypothalamus. (B1) Sagittal postcontrast T1-weighted MR image showing a typical Suprasellar stalk CP which is located extraventriclely and pushes hypothalamus upward. (B2) Intraoperative photograph showing that the specimen was obtained from the non-origin capsule of tumor attached to hypothalamus (white box). Yellow arrowheads indict the origin site of tumor which located in the lower part of stalk. (B3) Histopathological examination (×200) of tissue in the white box (B) showing that the non-origin capsule of tumor is full of tumor cells, without any hypothalamus tissues. (C1-3) Relationship between origin site of Hypothalamic stalk CP and pituitary stalk. (C1) Sagittal postcontrast T1-weighted MR image showing a Hypothalamic stalk CP which grows up to the third ventricle. (C2) Intraoperative photograph showing that the specimen was obtained from the inferior part of the tumor base attached to the top of stalk (white box). (C3) Histopathological examination (×200) of tissue in the white box (B) showing the invasion of the tumor tissue into pituitary stalk. (D1-3) Relationship between non-origin capsule of Hypothalamic stalk CP and pituitary stalk. (D1) Coronal postcontrast T1-weighted MR image showing a Hypothalamic stalk CP which pushes the anterior third ventricle to the right side. (D2) Intraoperative photograph showing that the specimen was obtained from the non-origin capsule of tumor closed to the stalk (white box). yellow arrowheads indicate the origin site of tumor. (D3) Histopathological examination (×200) of tissue in the white box (B) showing the clear boundary between tumor and pituitary stalk which is without any tumor cells invasion. N.II, optic nerve; Ht, hypothalamus; Tu, tumor. Ps, pituitary stalk.