Table 1 Comparison of sex-specific DMR calling on X chromosome using full and normalized datasets.

From: Dosage compensation and DNA methylation landscape of the X chromosome in mouse liver

 

X chromosome DMRs using all data

X chromosome DMRs using normalized data

Tool

#

overlap ‘normalized’ DMRs

#

overlap ‘all’ DMRs

DSS

1124

931

82.8%

1069

945

88.4%

Metilene

1342

1134

84.5%

1306

1242

95.1%

  1. Female versus male DMR calls for X chromosome were generated using both the new framework presented here (using normalized datasets) and the normal pipeline (using full datasets) with both the DSS and Metilene tools. Numbers of DMRs identified are listed along with numbers and percentages of overlapping DMRs.
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