Table 1 KEGG pathway enrichment analysis.

From: Identification of genes underlying the enhancement of immunity by a formula of lentinan, pachymaran and tremelia polysaccharides in immunosuppressive mice

Pathway

Pathway ID

All genes with pathway annotation (16857)

P-value

Differentially expressed genes

Cell adhesion molecules

ko04514

223 (1.32%)

0.0101

22329, 54725, 66871, 20970

Chemokine signaling

ko04062

281 (1.67%)

0.0091

12772, 12767, 66871

Primary immunodeficiency

ko05340

50 (0.3%)

9.42213e-05

16136, 12526, 12501

Staphylococcus aureus infection

ko05150

112 (0.66%)

2.150739e-07

12262, 246256, 14289, 12259, 14131

Systemic lupus erythematosus

ko05322

184 (1.09%)

6.912139e-05

12262, 16819, 246256, 12259, 14131, 12260

Natural killer cell mediated cytotoxicity

ko04650

256 (1.52%)

0.0001

15216, 14131, 246256, 22177, 14127, 224840

Fc gamma R-mediated phagocytosis

ko04666

187 (1.11%)

0.0342

246256, 14131, 66871

Phagosome

ko04145

344 (2.04%)

0.0501

246256, 14131, 17533

B cell receptor signaling

ko04662

147 (0.87%)

0.0064

213002, 66141

Transcriptional misregulation in cancer

ko05202

372 (2.21%)

0.0503

98752, 18507, 17394

Amino sugar and nucleotide sugar metabolism

ko00520

82 (0.49%)

0.0161

12655, 12654

  1. The differential genes enriched in KEGG biological pathway were analyzed by bioinformatics analysis tools (p < 0.05 by Fisher’s exact probability test). When p < 0.05, there are changes in biological functions related to certain biological pathways with those differential genes as representatives.
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