Figure 2
From: The functional and inflammatory response of brain endothelial cells to Toll-Like Receptor agonists
Characterization of hCMVEC secretion following administration of Imiquimod (5 µg/mL), LPS (100 ng/ml), Poly(I:C) (5 µg/mL), or media-only control at 48 hours. The concentration of soluble factors in the conditioned media was measured using multiplexed cytometric bead array. Cultured media was collected 72 hours following treatment and assayed using a cytokine panel chosen based on previous research17. Data shows the mean ± SD (n = 3). Significance compared to control (unless otherwise stated); *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
