Figure 6 | Scientific Reports

Figure 6

From: Fibroblast growth factor 12 is expressed in spiral and vestibular ganglia and necessary for auditory and equilibrium function

Figure 6

Expression and localisation of other FHFs mRNA in the inner ear. (a) Detection of FGF11, FGF13, and FGF14 mRNA expression by RT-PCR in cochleae of WT and FGF12-KO mice. β-actin positive controls are shown. (−) indicates reaction products without cDNA as a negative control. These gel images are cropped, and full-length images are presented in Supplementary Information 3. (b) Detection of FGF11, FGF13, and FGF14 mRNA expression by RT-PCR in vestibular ganglia of WT and FGF12-KO mice. (c,d) FGF11 mRNA localisation in the WT mouse inner ear by in situ hybridisation. (e,f) In situ hybridisation images on the WT mouse inner ear using the sense probe as a negative control. (g,h) FGF11 mRNA localisation in the FGF12-KO mouse inner ear by in situ hybridisation. (i,j) In situ hybridisation images of the FGF12-KO mouse inner ear using the sense probe as a negative control. Black triangles indicate spiral ganglions, and black arrows indicate vestibular ganglions in (c–j). Scale bar: 50 µm.

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