Table 1 Some clinical and laboratory data of the members of the UBRS082 family.

From: Loss-of-function mutations of SCN10A encoding NaV1.8 α subunit of voltage-gated sodium channel in patients with human kidney stone disease

Sample No.

Gender

Age

Age of Onset*

KUB result

Site/Side of stone

No. of stone

Treatment

Other Symptoms

Diagnosis

Dysuria

Hematuria

Pass Stone

Turbid Urine

II:1

Male

54

15

Negative

Unknown/ Right

N/A

Surgery

Yes

Yes

Yes

Yes

renal stone (surgical scar1)

II:2

Female

51

38

Positive

Ureter/ Right

1

Surgery

Yes

No

No

No

ureteric stone (KUB2)

II:4

Male

47

30

Positive

Renal/Right

1

No

Yes

No

Yes

Yes

renal stone (KUB)

II:5

Male

39

N/A

Positive

Renal/Left

1

No

No

No

No

No

renal stone (KUB)

II:6

Male

36

13

Positive

Renal/ Both

>5

No

Yes

No

No

No

renal stone (KUB)

III:2

Male

31

21

Positive

Renal/Left

>5

Surgery

Yes

No

No

No

renal stone (KUB)

III:4

Male

27

21

Negative

N/A

N/A

No

Yes

No

Yes

Yes

renal stone (strong clinical history3)

I:2

Female

76

 

Negative

  

No

No

No

No

No

no stone

II:3

Female

49

 

Negative

  

No

No

No

No

No

no stone

II:7

Female

35

 

Negative

  

No

No

No

No

No

no stone

II:8

Female

53

 

Negative

  

No

No

No

No

No

no stone

II:9

Female

45

 

Negative

  

No

Yes

Yes

No

No

no stone

II:10

Female

39

 

Negative

  

No

No

No

No

No

no stone

III:1

Male

33

 

Negative

  

No

No

No

No

No

no stone

III:3

Female

29

 

Negative

  

No

No

No

No

No

no stone

III:5

Male

17

 

Negative

  

No

No

No

No

No

no stone

III:6

Male

15

 

Negative

  

No

No

No

No

No

no stone

  1. 1The patient had surgical scar of kidney stone removal.
  2. 2The patient had positive results of kidney–ureter–bladder (KUB) radiography.
  3. 3The patient had strong clinical history as justified from the presence of several symptoms associated with kidney stone, especially hematuria and stone passage.
  4. *Age at the onset of kidney stone disease.