Figure 3

Antipruritic effect and detection in blood of MT intraperitoneal injection. (A) Like subcutaneous injection, intraperitoneal injection of 30 mg/kg MT also significantly decreased the scratching behavior induced by 200 mM histamine, 8 mM chloroquine and 13 mM compound 48/80, n = 4 in each group. ***P ≤ 0.001, unpaired student’s t-test. (B) Average plasma concentration-time relationships curves of MT after intraperitoneal or subcutaneous injection of 30 mg/kg MT, n = 3 in each time point. Group data presented by mean ± SEM.