Table 1 Comparisons of baseline characteristics between survivors and non-survivors.

From: Time-related association between fluid balance and mortality in sepsis patients: interaction between fluid balance and haemodynamics

Variables

Overall (n = 8584)

Survivors (n = 6706)

Non-survivors (n = 1878)

p

Age (years)

65.9 ± 16.0

64.9 ± 16.3

69.4 ± 14.3

<0.001

Male [n (%)]

3878 (45.1)

3064 (45.6)

814 (43.3)

0.071

Weight (kg)

82.1 ± 26.0

82.7 ± 26.3

80.0 ± 24.8

<0.001

Emergency [n (%)]

7811 (90.9)

5998 (89.4)

1813 (96.5)

<0.001

Ethnicity

  White [n (%)]

6150 (71.6)

4843 (72.0)

1307 (69.5)

0.026

  Black [n (%)]

662 (7.7)

546 (8.1)

116 (6.1)

0.005

  Asian [n (%)]

201 (2.3)

159 (2.4)

42 (2.2)

0.773

ICU types

  MICU [n (%)]

4075 (48.6)

3030 (45.0)

1045 (55.6)

<0.001

  SICU [n (%)]

998 (11.6)

883 (13.1)

115 (6.1)

<0.001

  CCU [n (%)]

1147 (13.3)

865(12.8)

282 (15.0)

0.017

Infection sites

  Respiratory [n (%)]

5117 (59.6)

3858 (57.5)

1259 (67.0)

<0.001

  Urinary [n (%)]

2780 (32.3)

2326 (34.7)

454 (24.1)

<0.001

  Bloodstream [n (%)]

3038 (35.4)

2076 (30.8)

962 (51.2)

<0.001

  Abdominal [n (%)]

1113 (12.9)

877 (13.0)

236 (12.5)

0.560

  Intracranial [n (%)]

607 (7.1)

501 (7.6)

106 (5.6)

0.006

Laboratory indexes

  Maximum serum creatinine

2.19 ± 2.19

2.03 ± 2.21

2.76 ± 2.03

<0.001

  Minimum serum haemoglobin

8.56 ± 1.72

8.63 ± 1.70

8.31 ± 1.76

<0.001

  Maximum serum lactate

3.40 ± 3.17

2.90 ± 2.35

4.95 ± 4.58

<0.001

  Maximum serum sodium

144.4 ± 5.2

144.2 ± 4.9

145.1 ± 6.1

0.001

  Maximum white blood cell count

20.9 ± 12.5

20.3 ± 14.1

23.3 ± 15.3

<0.001

Clinical characteristics

  SOFA at ICU admission [median (IQR)]

5 (4–8)

5 (3–7)

6 (4–9)

<0.001

  Fluid balance (ml/kg/48hr)

40.5 ± 56.7

34.9 ± 53.4

60.2 ± 63.2

<0.001

  Fluid balance (ml/kg/first-24hr)

28.3 ± 40.6

26.1 ± 39.3

36.3 ± 44.1

<0.001

  Fluid balance (ml/kg/second-24hr)

12.1 ± 28.3

8.8 ± 26.3

23.9 ± 31.8

<0.001

  Fluid intake (ml/kg/48 hr)

93.91 ± 58.2

91.3 ± 55.6

103.5 ± 64.7

<0.001

  Intravenous fluid intake (ml/kg/48 hr)

84.8 ± 58.6

81.8 ± 56.3

95.6 ± 64.7

<0.001

  Output (ml/kg/48 hr)

53.5 ± 35.0

56.3 ± 34.9

43.3 ± 33.7

<0.001

  Urine output (ml/kg/48 hr)

43.1 ± 30.2

45.9 ± 30.2

32.9 ± 28.1

<0.001

  Haemodialysis

969 (11.2)

638 (9.5)

331 (17.6)

<0.001

  Vasopressor-use

2513 (29.2)

1846 (27.5)

667 (35.5)

<0.001

  1. Abbreviations: MICU, medical intensive care unit; SICU, surgical intensive care unit; CCU, coronary care unit; SOFA sequential organ failure assessment; ICU, intensive care unit; IQR, interquartile range.
Back to article page