Table 4 Adjusted odds ratio of mortality using fluid balance as design variables in logistic models.

From: Time-related association between fluid balance and mortality in sepsis patients: interaction between fluid balance and haemodynamics

Variables

Odds ratio (95% CI)

p

Odds ratio (95% CI)

p

Odds ratio (95% CI)

p

All patients

  Model 1

All FB-fir24hr (n = 8584)

All FB-sec24hr (n = 8584)

All FB-48hr (n = 8584)

   

  FB Q1

1

1

1

  FB Q2

1.05 (0.89–1.23)

0.540

1.56 (1.31–1.86)

<0.001

1.20 (1.01–1.42)

0.035

  FB Q3

1.11 (0.95–1.31)

0.164

1.94 (1.64–2.31)

<0.001

1.57 (1.33–1.85)

<0.001

  FB Q4

1.41 (1.20–1.65)

<0.001

3.33 (2.82–3.92)

<0.001

2.31 (1.88–2.59)

<0.001

Patients with negative FB

  Model 1

Negative FB-fir24hr (n = 1882)

Negative FB-sec24hr (n = 2866)

Negative FB-48hr (n = 1950)

   

  FB Q1

1

1

1

  FB Q2

0.86 (0.61–1.21)

0.391

0.97 (0.72–1.32)

0.891

0.87 (0.61–1.24)

0.459

  FB Q3

0.88 (0.62–1.24)

0.480

0.62 (0.44–0.86)

0.005

0.74 (0.52–1.07)

0.115

  FB Q4

0.77 (0.54–1.09)

0.145

0.59 (0.43–0.82)

0.002

0.53 (0.36–0.78)

<0.001

  1. Abbreviation: FB-fir24hr, FB-sec24hr, and FB-48hr represented the fluid balance within the first 24 hours, the second 24 hours and the 48 hours after ICU admission, respectively.
  2. Note: All three models were adjusted for infection site, disease severity score, haemodialysis, and laboratory factors (including serum creatinine, sodium, calcium and platelet count).