Table 1 Patient background-Obese and non-obese subjects-.

From: Down-regulation of vascular GLP-1 receptor expression in human subjects with obesity

 

Obese (n = 16)

(BMI ≥ 25 kg/m2)

Non-obese (n = 24)

(BMI < 25 kg/m2)

p

Arterial dissection/Aneurysm/ ASO/Amputation/etc.

11/5/0/0/0

9/7/6/1/1

 

Diabetes/Non-diabetes

5/11 (31.3%)

6/17 (26.1%)

n.s.

With hypertension

5 (31.3%)

7 (29.2%)

n.s.

With ARB or ACE-I

4 (25.0%)

3 (12.5%)

n.s.

With Ca-blockers

3 (18.8%)

4 (16.7%)

n.s.

With dyslipidemia

13 (81.3%)

19 (79.2%)

n.s.

With statin

3 (18.8%)

8 (33.3%)

n.s.

With anti-coagulant drugs

0 (0%)

4 (16.7%)

0.036

Age

61.4 ± 16.7

72.1 ± 9.1

0.047

BMI (kg/m2)

28.6 ± 2.5

20.7 ± 2.8

<0.0001

HbA1c (%)

5.9 ± 0.6

6.4 ± 1.9

n.s.

Fasting plasma glucose (mg/dl)

121.2 ± 32.2

116.6 ± 25.0

n.s.

LDL cholesterol (mg/dl)

111.1 ± 38.1

91.3 ± 33.0

n.s.

HDL cholesterol (mg/dl)

37.1 ± 10.3

39.0 ± 9.0

n.s.

C-reactive protein (mg/dl)

2.3 ± 1.0

1.9 ± 0.6

n.s.

  1. Abbreviations: ARB, angiotensin II receptor blocker; ACE-I, angiotensin converting enzyme inhibitor; ASO, arteriosclerosis obliterans; BMI, body mass index; LDL, low-density lipoprotein; HDL, high-density lipoprotein; n.s. not significant.