Figure 2

Effects of MKEY treatment on heart function after I/R. Representative images of echocardiography (A) and quantification of ejection fraction (B) cardiac output (C) and preserved systolic (D) ventricular dimensions in MKEY-treated, compared to sMKEY-treated control mice, one week after I/R. Left ventricular developed pressure (E) and contraction (F) as well as the response to dobutamine stimulation (white bars E,F), were assessed using intraventricular Millar catheter. #p < 0.05 vs. sham; *p < 0.05 vs. control; §p < 0.05 vs. unstimulated (n = 10).